Table 3.
Significant relation between clinical parameters and gene expressions of CYP2E1 and Caspase-3.
Parameters (normal range) | CYP2E1 (2–∆∆Ct) (Mean) |
p | Caspase-3 (2–∆∆Ct) (Mean) |
p |
---|---|---|---|---|
Age (years) | ||||
<50 | 2.03157 | **0.0012 | 3.09647 | **0.0095 |
≥50 | 0.628595 | 1.52784 | ||
Effected lung | 0.623731 | ***0.0001 | 1.42367 | **0.0030 |
Unaffected lung | 1.86532 | 3.09569 | ||
Lymphocytes (×109/L; 1.21–3.77) | ||||
Low | 0.585651 | **0.0070 | 0.859153 | ***0.0009 |
Normal | 1.26119 | 2.50666 | ||
Platelets (×109/L; 152–383) | ||||
Low | 0.412991 | ⁎0.0111 | 0.897469 | ⁎0.0277 |
Normal | 1.23811 | 2.3335 | ||
High | 0.824631 | 1.85276 | ||
Total bilirubin (mg/dL; 0.2–1.1) | ||||
Normal | 1.23365 | ⁎0.0378 | 2.33736 | ⁎0.0278 |
High | 0.414558 | 0.809643 | ||
Lactate dehydrogenase (U/L; 120–246) | ||||
Normal | 1.25268 | ⁎0.0172 | 2.51968 | ⁎0.0550 |
High | 0.903975 | 1.60952 |
BUN; blood urea nitrogen; Mann Whitney U test was used to all parameters.
p < 0.05 was considered statically significant