Table 1.

Averaged percentage of injected dose/mL (%ID/mL) for [¹⁸F]F-DPA, [¹⁸F]DPA-714, and [¹¹C]PBR28 at peak uptake and 60 min after injection, together with peak/60 min ratios

	[18F]F-DPA			[18F]DPA-714			[11C]PBR28
	Peak	60 min	Peak/60 min	Peak	60 min	Peak/60 min	Peak	60 min	Peak/60 min
Brain	4.83	1.37	3.52	2.69	1.79	1.50 ***	3.59	1.89	1.90***
Cortex	4.26	1.17	3.64	2.35	1.51	1.55 ***	3.13	1.60	1.95 ***
Hippocampus	4.84	1.13	4.27	2.94	1.68	1.75 ***	3.89	1.72	2.26 ***
Striatum	4.72	1.07	4.41	2.57	1.46	1.76 ***	3.64	1.59	2.29 ***
Thalamus	5.29	1.05	5.02	3.02	1.54	1.96 ***	4.10	1.63	2.52 ***

Averaged %ID/mL for [¹⁸F]F-DPA, [¹⁸F]DPA-714, and [¹¹C]PBR28 (n = 5–6) at peak uptake and 60 min after injection, together with peak/60-min ratios for whole brain, cortex, hippocampus, striatum, and thalamus in wild-type (WT) mice. * denotes significant differences between [¹⁸F]F-DPA peak/60-min ratios and [¹⁸F]DPA-714 and [¹¹C]PBR28 peak/60-min ratios. # denotes significant differences between [¹⁸F]DPA-714 peak/60-min ratios and [¹¹C]PBR28 peak/60-min ratios. *p < 0.05, ** p < 0.01, *** p < 0.001, ^#p < 0.05