Table 5.

Pharmacokinetic properties of identified compounds from the aqueous extract of S. torvum unripe fruits

Compound no	Compound name	Lipinski	BBB	HIA	PGP-	Bioavailability score
1	Ergost-25-ene-3,6-dione, 5,12-dihydroxy-, (5.alpha.,12.beta.)-	Yes	No	High	No	0.55
2	Aspidospermidin-17-Ol, 1-Acetyl-16-Methoxy-	Yes	Yes	High	Yes	0.55
3	2-[3,4-Dichlorophenyl]-4-[[2-[1-methyl-2-pyrrolidinyl]ethyl]amino]-6-[trichloromethyl]-S-triazine	Yes	Yes	High	Yes	0.55
4	Dihydroartemisinin, 10-O-(t-butyloxy)-	Yes	Yes	High	Yes	0.55
5	3-[(2-fluoroanilino)methyl]-5-(2-methoxyphenyl)-1,3,4-oxadiazole-2(3 h)-thione	Yes	No	High	Yes	0.55
6	2(1H)-naphthalenone, 5-[2-(3-furanyl)ethyl]octahydro-1,5,6,8a-tetramethyl-,	Yes	Yes	High	Yes	0.55
7	4H-1-benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5-dihydroxy-7-methoxy-	Yes	No	High	Yes	0.55
8	2-butenoic acid, 2-methyl-, 4,4a,5,6,7,8,8a,9-octahydro-8a-hydroxy-3,4a,5-trimethylnaphtho[2,3-b]furan-6-yl ester	Yes	Yes	High	Yes	0.55
9	Benzonitrile, 4-(4-ethylcyclohexyl)-, trans-	Yes	Yes	High	Yes	0.55
10	1-(2-adamantylidene) semicarbazide	Yes	Yes	High	No	0.55
11	Doxorubicin (synthetic drug)	No	No	Low	NA	0.17