Table 2.
Comparison of clinical features, aetiology and treatment in patients admitted for AGE in 2019 and in 2012
| 2019 (n = 86) | 2012 (n = 85) |
p | |
|---|---|---|---|
|
Age, years Range |
Median 2.5 [IQR 1.4–5.9] 22 days–17.8 years | Median 2.3 [IQR 1.3–5.1] 2 months–17.5 years | n.s |
| Males, n (%) | 47 (55) | 42 (49) | n.s |
| Length of hospital stay, days | 3.1 ± 1.4 | 3.7 ± 2.2 | 0.03 |
| Diarrhoea, n (%) | 79 (92) | 72 (85) | n.s |
| Vomiting, n (%) | 73 (85) | 69 (81) | n.s |
| Fever (TC > 37.5 °C), n (%) | 49 (57) | 26 (31) | < 0.001 |
| Nausea, n (%) | 31 (36) | 21 (25) | n.s |
| Abdominal pain, n (%) | 18 (21) | 22 (26) | n.s |
| Decreased skin turgor, n (%) | 46 (54) | 29 (34) | 0.01 |
| Microbiological investigations on stool samples, n (%) | 74 (86) | 64 (75) | n.s |
|
- Viral infection Rotavirus Adenovirus Norovirus Astrovirus |
18/74 (24) 4/18 (22) 9/18 (50) 4/18 (22) 1/18 (6) |
30/64 (47) 20/30 (67) 3/30 (10) 6/30 (20) 1/30 (3) |
0.005 0.003 0.002 n.s n.s |
|
- Bacterial infection Non-Typhi Salmonella Campylobacter jejuni Yersinia enterocolitica Escherichia coli |
12/74 (16) 4/12 (33) 6/12 (50) 1/12 (8) 1/12 (8) |
8/64 (13) 5/8 (63) 3/8 (38) 0 0 |
n.s n.s n.s n.s n.s |
| - Viral-Bacterial coinfection |
2/74 (3) Astrovirus and non-typhi Salmonella |
1/64 (2) Rotavirus and non-typhi Salmonella |
n.s |
| - Negative | 42/74 (58) | 25/64 (39) | 0.04 |
| IV fluid therapy alone, n (%) | 36 (42) | 56 (66) | 0.002 |
| IV fluid therapy after ORS failure, n (%) | 25 (29) | 11 (13) | 0.009 |
| ORS alone, n (%) | 15 (17) | 6 (7) | 0.04 |
| Gradual refeeding, n (%) | 10 (12) | 12 (14) | n.s |
| Length of IV fluid therapy, days | 2.4 (1) | 2.3 (1) | n.s |
IV intravenous, ORS oral rehydration solution