Table 3.
Results of the application of the method to the plasma samples (n = 38). Data are reported as median and 5th and 95th percentiles, along with the number (and percentage) of samples with concentrations greater than or equal to the lower limit of quantitation
| Analyte | 5th percentile (µg/L) |
Median (µg/L) |
95th percentile (µg/L) |
Samples ≥ LLOQ (percentage) |
|---|---|---|---|---|
| PFBA | < LLOQ | < LLOQ | 0.104 | 3 (8%) |
| PFPeA | < LLOQ | < LLOQ | < LLOQ | 0 (0%) |
| PFHxA | < LLOQ | < LLOQ | < LLOQ | 0 (0%) |
| PFHpA | < LLOQ | < LLOQ | 0.194 | 18 (47%) |
| PFOA | 0.952 | 1.497 | 3.565 | 38 (100%) |
| PFNA | 0.274 | 0.409 | 0.748 | 38 (100%) |
| PFDA | 0.106 | 0.198 | 0.329 | 38 (100%) |
| PFUnDA | < LLOQ | 0.139 | 0.310 | 29 (76%) |
| PFDoDA | < LLOQ | < LLOQ | 0.058 | 5 (13%) |
| PFTrDA | < LLOQ | 0.031 | 0.073 | 27 (71%) |
| PFTeDA | < LLOQ | <LLOQ | < LLOQ | 1 (3%) |
| PFOSA | < LLOQ | < LLOQ | < LLOQ | 1 (3%) |
| N-MeFOSAA | < LLOQ | < LLOQ | 0.050 | 3 (8%) |
| N-EtFOSAA | < LLOQ | < LLOQ | < LLOQ | 1 (3%) |
| PFBS | < LLOQ | < LLOQ | 0.086 | 10 (26%) |
| PFPeS | < LLOQ | 0.029 | 0.076 | 28 (74%) |
| n-PFHxS: linear isomer | 0.275 | 0.580 | 1.692 | 38 (100%) |
| PFHxS: Ʃ branched isomers | < LLOQ | 0.035 | 0.079 | 35 (92%) |
| PFHpS | < LLOQ | 0.093 | 0.249 | 29 (76%) |
| n-PFOS: linear isomer | 1.113 | 1.909 | 4.679 | 38 (100%) |
| PFOS: Ʃ branched isomers | 0.612 | 1.267 | 3.279 | 38 (100%) |
| PFNS | < LLOQ | <L LOQ | < LLOQ | 0 (0%) |
| PFDS | < LLOQ | < LLOQ | < LLOQ | 0 (0%) |
| PFECHS | 0.021 | 0.041 | 0.135 | 38 (100%) |
| 4:2-FTSA | < LLOQ | < LLOQ | < LOQ | 0 (0%) |
| 6:2 FTSA | < LLOQ | < LLOQ | < LOQ | 1 (3%) |
| 8:2 FTSA | < LLOQ | < LLOQ | < LOQ | 1 (3%) |
| HFPO-DA | < LLOQ | < LLOQ | < LOQ | 0 (0%) |
| DONA | < LLOQ | < LLOQ | < LOQ | 0 (0%) |
| cC6O4 | < LLOQ | < LLOQ | < LOQ | 1 (3%) |
| 6:2 Cl-PFESA | < LLOQ | < LLOQ | 0.020 | 6 (16%) |
| 8:2 Cl-PFESA | < LLOQ | < LLOQ | < LùLOQ | 0 (0%) |
For calculation of the median and 5th and 95th percentiles, the non-quantifiable values were replaced with half of the LLOQ. Replacement values were the following: PFBA: 0.039; PFPeA: 0.010; PFHxA: 0.020; PFHpA: 0.020; PFOA: 0.078; PFNA: 0.039; PFDA: 0.039; PFUnDA: 0.039; PFDoDA: 0.020; PFTrDA: 0.010; PFTeDA: 0.010; PFOSA: 0.005; N-MeFOSAA: 0.020; N-EtFOSAA: 0.020; PFBS: 0.018; PFPeS: 0.009; n-PFHxS: 0.058; PFHxS Ʃ branched isomers: 0.006; PFHpS: 0.037; n-PFOS: 0.114; PFOS Ʃ branched isomers: 0.122; PFNS: 0.019; PFDS: 0.010; PFECHS: 0.004; 4:2 FTSA: 0.009; 6:2 FTSA: 0.010; 8:2 FTSA: 0.019; HFPO-DA: 0.010; DONA: 0.009; cC6O4: 0.010; 6:2 Cl-PFESA: 0.009; and 8:2 Cl-PFESA: 0.004 µg/L