Figure 3.

Cortical thickness, white matter lesions and placebo response. (A) Precuneus region whose thickness dimensionally predicts a stronger placebo response as depicted in the scatterplot. (B) Lesion probability maps in placebo responders (red) and non-responders (blue): no significant differences in lesion location between groups. (C) Cortical areas whose thickness was significantly associated with lesion load in the placebo non-responders. (D) Mean cortical thickness of the regions shown in relation to white matter lesion load (FLAIR) in the placebo responders (red) and non-responders (blue). A mask of the regions shown in C was used to extract mean CT values across these regions for all participants.