Table 1.
The basic clinical characteristics of young and middle-aged men with normal fasting glucose by blood pressure status.
| Characteristics | Young men | Middle-aged men | ||||
|---|---|---|---|---|---|---|
| Non-hypertension | ISH | p value | Non-hypertension | ISH | p value | |
| No., n (%) | 2252 | 163 (6.7) | – | 5573 | 258 (4.4) | – |
| Age (year) | 29.8 ± 3.8 | 29.9 ± 3.7 | 0.739 | 42.9 ± 4.6 | 42.5 ± 4.8 | 0.253 |
| Smoking (%) | 21.6% | 19.3% | 0.553 | 34.4% | 26.7% | 0.029 |
| Drinking (%) | 15.9% | 17.6% | 0.609 | 25.8% | 29.3% | 0.283 |
| NAFL (%) | 17.5% | 20.8% | 0.021 | 20.1% | 24.2% | 0.036 |
| BMI (kg/m2) | 23.5 ± 3.3 | 25.7 ± 4.4 | < 0.001 | 24.0 ± 2.9 | 25.5 ± 3.2 | < 0.001 |
| WC (cm) | 80.2 ± 8.7 | 85.2 ± 11.5 | < 0.001 | 82.5 ± 7.5 | 85.8 ± 8.5 | < 0.001 |
| WHR | 0.84 ± 0.05 | 0.86 ± 0.07 | < 0.001 | 0.87 ± 0.05 | 0.89 ± 0.05 | < 0.001 |
| WHtR | 0.46 ± 0.05 | 0.49 ± 0.07 | < 0.001 | 0.48 ± 0.04 | 0.50 ± 0.05 | < 0.001 |
| SBP (mmHg) | 120.2 ± 11.1 | 144.7 ± 5.1 | < 0.001 | 118.3 ± 11.1 | 145.9 ± 5.9 | < 0.001 |
| DBP (mmHg) | 72.1 ± 8.1 | 81.3 ± 5.6 | < 0.001 | 74.7 ± 8.0 | 83.8 ± 4.8 | < 0.001 |
| HR (beats/min) | 79.1 ± 12.2 | 85.3 ± 12.9 | < 0.001 | 76.2 ± 11.0 | 82.2 ± 12.3 | < 0.001 |
| FPG (mmol/L) | 5.17 ± 0.29 | 5.21 ± 0.25 | < 0.001 | 5.20 ± 0.28 | 5.27 ± 0.29 | 0.001 |
| UA (μmol/L) | 389.9 ± 75.5 | 398.9 ± 78.4 | 0.143 | 381.2 ± 72.7 | 393.7 ± 79.3 | 0.007 |
| TC (mmol/L) | 4.50 ± 0.80 | 4.68 ± 0.78 | 0.006 | 4.77 ± 0.85 | 4.79 ± 0.96 | 0.651 |
| TG (mmol/L) | 1.30 ± 0.86 | 1.53 ± 1.12 | 0.002 | 1.71 ± 1.42 | 1.85 ± 1.21 | 0.113 |
| HDLc (mmol/L) | 1.42 ± 0.28 | 1.39 ± 0.33 | 0.141 | 1.39 ± 0.29 | 1.34 ± 0.27 | 0.006 |
| LDLc (mmol/L) | 2.47 ± 0.68 | 2.56 ± 0.70 | 0.122 | 2.64 ± 0.71 | 2.67 ± 0.79 | 0.520 |
| ALT (U/L) | 31.4 ± 25.3 | 36.1 ± 26.5 | 0.025 | 31.0 ± 25.2 | 36.4 ± 25.2 | 0.001 |
| AST (U/L) | 22.3 ± 10.5 | 23.9 ± 11.7 | 0.062 | 22.5 ± 11.7 | 24.1 ± 9.4 | 0.029 |
| ALP (U/L) | 67.7 ± 18.1 | 67.0 ± 16.9 | 0.661 | 67.5 ± 16.5 | 69.0 ± 16.7 | 0.168 |
| GGT (U/L) | 30.2 ± 23.4 | 35.4 ± 33.2 | 0.009 | 38.7 ± 36.2 | 46.1 ± 39.0 | 0.001 |
| Insulin (μU/mL) | 9.83 ± 5.95 | 12.57 ± 8.00 | < 0.001 | 9.36 ± 5.14 | 11.73 ± 6.35 | < 0.001 |
| HOMA-IR | 2.27 ± 1.38 | 2.92 ± 1.91 | < 0.001 | 2.18 ± 1.22 | 2.75 ± 1.48 | < 0.001 |
| TyG | 8.44 ± 0.51 | 8.56 ± 0.65 | 0.007 | 8.69 ± 0.55 | 8.79 ± 0.56 | 0.003 |
| METS-IR | 33.7 ± 6.3 | 37.6 ± 8.6 | < 0.001 | 35.3 ± 6.0 | 38.1 ± 6.7 | < 0.001 |
NAFL nonalcoholic fatty liver, BMI body mass index, WC waist circumference, WHR waist to hip ratio, WHtR waist to height ratio, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, FPG fasting plasma glucose, UA plasma uric acid, TC total cholesterol, TG triglyceride, HDLc high-density lipoprotein cholesterol, LDLc low-density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma glutamyltranspeptidase, HOMA-IR homeostasis model assessment for IR index, TyG triglyceride glucose index, METS-IR metabolic score for IR.