Table 2.
Characteristics of patients with early-onset disease.
| All patients (n=88) | |
|---|---|
| Gestational age (weeks) | 39+3 (37+3–40+4) |
| Female | 42 (47·7) |
| Apgar score at 5 min | 10 (9–10) |
| Apgar score <7 at 5 min | 12 (13·6) |
| Birth weight (kg) | 3·4 (2·9–3·8) |
| Day of culture | 0 (0–1) |
| Onset of symptoms <24 h | 67 (76·1) |
| Diagnosis | |
| Sepsis | 77 (87·5) |
| Meningitis | 11 (12·5) |
| Causative pathogen | |
| GBS | 81 (92·0) |
| E. coli | 7 (8·0) |
| Positive CSF culture | 11/64 (17·2) |
| CSF leukocytes (106/L) | 5991 (3218–9587) |
| <1000 | 0/8 (0) |
| 1000–10 000 | 6/8 (75·0) |
| ≥10 000 | 2/8 (25·0) |
| CSF Glucose (mmol/L) | 0.2 (0·1–1·2) |
| CSF Protein (g/L) | 4.0 (2.8–5.0) |
| ≥1 Spanos criterion* | 8/8 (100) |
| Highest CRP (mg/L) | 103 (46–147) |
| Transfer to intensive care unit | 20 (22·7) |
| Deaths | 1 (1·1) |
Numbers are presented as n (%) or median (IQR). *Spanos criteria: CSF glucose <1·9 mmol/L; CSF-blood glucose ratio <0·23; CSF protein >2·2 g/L; CSF WBC count >2000 × 106/L; CSF neutrophil count >1180 106/L.