Table 4.

FDA-approved drugs used for COVID-19 treatment with low binding affinity score than Parthenolide and are used as medicine

Protein of COVID-19	Ligand	Binding affinity (kcal/mol)	References
4OVZ	Chloroquine	-7.0	(Patel 2020)
	Favipiravir	-6.5	(Prajapat 2020)
	Interferon	-8.2	(Huang 2020)
	Ribavirin	-7.4	(Ran 2020)