Table 4.

Multiple Linear Regression Models^# predicting the difference of means for each variable of interest between hyperuricemic and normouricemic groups

	$Model 1				$Model 2
Parameter	Coefficient	95% CI	p-value	R2	Coefficient	95% CI	p-value	R2
Hemoglobin (g/dL)	-0.12	(-0.35, 0.11)	0.315	0.56	-0.14	(-0.39, 0.10)	0.259	0.57
Folate (nmol/L)	-0.55	(-1.81, 0.70)	0.389	0.03	-0.37	(-1.67, 0.93)	0.576	0.04
RBC (106/µL)	0.04	(-0.04, 0.12)	0.362	0.37	-0.01	(-0.10, 0.08)	0.785	0.35
TIBC (µmol/L)	0.07	(-1.54, 1.68)	0.934	0.18	0.00	(-1.72, 1.72)	0.999	0.19
WBC (103/µL)	0.16	(-0.20, 0.51)	0.386	0.00	-0.12	(-0.50, 0.26)	0.534	0.04
Monocytes (%)	-0.01	(-0.34, 0.32)	0.960	0.06	0.19	(-0.17, 0.54)	0.298	0.06
Platelet (103/µL)	8.82	(-2.32, 19.96)	0.121	0.11	-0.38	(-12.30, 11.54)	0.950	0.13
HDL (mmol/L)	-0.14	(-0.20, -0.08)	<0.001	0.21	-0.07	(-0.14, -0.01)	0.019	0.26
LDL (mmol/L)	0.18	(0.05, 0.31)	0.008	0.11	0.13	(-0.01, 0.27)	0.065	0.11
Triglycerides (mmol/L)	0.20	(0.09, 0.31)	0.001	0.13	0.12	(-0.01, 0.25)	0.066	0.15
C-peptide (ng/mL)	0.75	(0.46, 1.04)	<0.001	0.05	0.38	(0.06, 0.69)	0.018	0.12
Glucose (mmol/L)	0.15	(0.02, 0.28)	0.021	0.05	0.06	(-0.08, 0.21)	0.395	0.07
HbA1c (%)	0.10	(0.02, 0.17)	0.011	0.04	0.04	(-0.04, 0.12)	0.358	0.07
*Ferritin (Males) (µg/L)	16.01	(1.93, 30.09)	0.026	0.04	8.08	(-7.18, 23.34)	0.298	0.07
*Ferritin (Females) (µg/L)	15.06	(0.19, 29.93)	0.047	0.01	13.72	(-0.27, 27.7)	0.054	0.00
MHR	0.62	(0.25, 1.00)	0.001	0.21	0.47	(0.06, 0.89)	0.026	0.21

^#The linear regression models were constructed using categorical uric acid groups where normouricemics were labeled 0 and hyperuricemics were labeled 1, and thus the coefficients displayed indicate the mean difference in the outcome variables between the hyperuricemic and normouricemic groups.

^$Model 1 is adjusted for age groups and sex. Model 2 is adjusted for age groups, sex, BMI, smoking and exercise. Adjusted R2 values have been displayed.

*The regression models pertaining to ferritin were stratified by sex to avoid model misspecification.