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. 2022 Jan 15;20:26. doi: 10.1186/s12967-021-03222-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Resting state global efficiency of the sensorimotor network. a The sensorimotor network comprised the precentral gyrus (PreCG), postcentral gyrus (PostCG), superior parietal lobule (SPL), anterior supramarginal gyrus (aSMG), posterior supramarginal gyrus (pSMG), angular gyrus (AG), superior lateral occipital cortex (sLOC), and the parietal operculum (PO). These anatomical ROIs were defined according to the Harvard–Oxford-atlas. b In the stimulated left-hemispheric sensorimotor network, global efficiency values were significantly higher in the verum compared to the sham condition. Significant hubs within the network are represented by red spheres weighted according to the T value for the contrast between the conditions (FDR 0.05 corr.). No effects were detected in the non-stimulated right hemisphere