TABLE 2.
PCR results for patients and controls from the United States and Denmarka
| Type of result | CD
|
UC
|
Control
|
|||
|---|---|---|---|---|---|---|
| US | DK | US | DK | US | DK | |
| Total no. of patients tested | 30 | 49 | 35 | 26 | 18 | 30 |
| Total no. of tissues tested | 175 | 312 | 212 | 158 | 98 | 91 |
| Mean ± SD (range) of tissues tested per patient | 5.8 ± 2.1 (1–12) | 6.4 ± 0.8 (4–7) | 6.1 ± 1.4 (3–9) | 6.1 ± 0.8 (3–7) | 5.4 ± 1.6 (2–9) | 3.0 ± 1.5 (2–7) |
| No. (range) of positive tissues per patient | 0–4 | 0–3 | 0–3 | 0–2 | 0–1 | 0–1 |
| No. (%) of total tissues positive | 15 (8.6) | 10 (3.2) | 21 (9.9) | 7 (4.4) | 1 (1.0) | 2 (2.2) |
| No. (%) of patients positive | 9 (30.0) | 6 (12.2) | 12 (34.3) | 4 (15.4) | 1 (5.6) | 2 (6.7) |
Abbreviations: US, United States; DK, Denmark. Significance: among U.S. groups, CD versus controls, P = 0.07; OR = 7.29 (0.84–63.38); UC versus controls, P = 0.04; OR = 8.87 (1.05–74.99); IBD versus controls, P = 0.03; OR = 8.11 (1.01–65.16); among Denmark groups, no significant differences; among U.S. and Denmark combined groups, CD versus controls, P = 0.06; OR = 3.52 (0.96–12.86); UC versus controls, P = 0.01; OR = 5.33 (1.45–19.59); IBD versus controls, P = 0.02; OR = 4.27 (1.24–14.67). Fisher's exact test, two sided, was used (95% confidence interval). The number tested was less than total number in study for some groups due to failure to acquire samples. The positive rates by group, shown as number positive/total number (percent), are 15/79 (19.0), 16/61 (26.2), and 3/48 (6.3) for CD, UC, and control groups, respectively. The positive rate overall for all IBD patients (CD plus UC) was 31 positive of 140 total (22.1%).