TABLE 6.
IL-5 levels in PBMC culture supernatants after stimulation with mycobacterial antigens or PHA for Danish outpatient study groups, excluding those not BCG vaccinateda
| Antigen or mitogen | Value type | Level (pg/ml) for group (n):
|
||
|---|---|---|---|---|
| CD (56) | UC (64) | Control (63) | ||
| M. avium PPD | Median | 12.5 | 1.0 | 1.0 |
| Mean ± SEM | 141 ± 31 | 117 ± 33 | 72 ± 22 | |
| Range | 1–941 | 1–1,538 | 1–1,097 | |
| M. bovis PPD | Median | 3.0 | 1.0 | 1.0 |
| Mean ± SEM | 213 ± 49 | 73 ± 16 | 144 ± 82 | |
| Range | 1–1,522 | 1–509 | 1–5,181 | |
| TT | Median | 245 | 195* | 532 |
| Mean ± SEM | 555 ± 85 | 535 ± 96 | 698 ± 74 | |
| Range | 1–2,126 | 0–4,508 | 1–1,995 | |
a
Kruskal-Wallis nonparametric ANOVA with Dunn's multiple comparisons test. *, among all group comparisons for all antigens, only IL-5 release by UC patient PBMCs in response to TT was lower than controls (P < 0.05).