Table 1.

Examples of FDA-approved nanomedicines

Trade name	Material description	Advantages	Indications	Approval year
Estrasorb™	Micellar Estradiol	Controlled delivery of the drug	Menopausal therapy	2003
Marqibo®	Liposomal Vincristine	Increased delivery to tumor tissue; decreased systemic toxicity resulting from side-effects	Acute lymphoblastic leukemia	2012
Onivyde®	Liposomal Irinotecan		Pancreatic cancer	2015
BNT162b2 vaccine (developed by BioNTech and Pfizer)	Nucleoside modified mRNA encoding the viral spike glycoprotein of SARS-CoV-2, encapsulated in lipid nanoparticles	Protection of the non-replicating RNA from degradation and allow it to be delivered into host cells after intramuscular injection	Prevention of coronavirus disease	2020
mRNA-1273 vaccine (developed by Moderna)	Lipid nanoparticle-encapsulated mRNA-based vaccine, which encodes the spike protein (S protein) of SARS-CoV-2	Lipid nanoparticles are playing a key role in protecting and transporting the mRNA effectively to the right place in cells	Prevention of coronavirus disease	2020