TABLE 2.
Patient Demographics and Clinical Characteristics
| CAD+Patients (n = 35) |
CAD-Patients (n = 45) |
Healthy Volunteers (n = 17) |
|
|---|---|---|---|
| Risk factors for CAD | |||
| Male | 21 (60.0) | 21 (46.7) | 15 (88.2) |
| Age, yrs | 62.3 ± 11.0 | 53.8 ± 13.3 | 23.0 ± 7.3 |
| Body mass index, kg/m2 | 27.8 ± 5.1 | 28.3 ± 7.5 | 25.1 ± 3.0 |
| Current smokers | 6 (17.1) | 3 (6.7) | 0 (0.0) |
| Hypertension | 30 (85.7) | 25 (55.6) | 0 |
| Diabetes | 8 (22.9) | 8 (17.8) | 0 |
| Hyperlipidemia | 31 (88.6) | 25 (55.6) | 0 |
| Total cholesterol, mg/dl | 156.5 ± 36.7 | 180.4 ± 38.8 | 146.5 ± 33.4 |
| LDL cholesterol, mg/dl | 77.8 ± 33.2 | 100.0 ± 33.3 | 85.9 ± 30.6 |
| HDL cholesterol, mg/dl | 45.3 ± 14.8 | 54.5 ± 19.5 | 47.7 ± 15.5 |
| Triglyceride, mg/dl | 129.6 ± 54.0 | 102.2 ± 54.3 | 64.8 ± 29.9 |
| Medications | 33 (94.3) | 34 (75.6) | 0 |
| Statin | 28 (80.0) | 20 (44.4) | 0 |
| Beta-blocker | 21 (60.0) | 12 (26.7) | 0 |
| Aspirin | 26 (74.3) | 17 (37.8) | 0 |
| ACE inhibitor | 18 (51.4) | 12 (26.7) | 0 |
| Calcium channel blocker | 5 (14.3) | 5 (11.1) | 0 |
| Nitrate | 7 (20.0) | 3 (6.7) | 0 |
| CAD status | |||
| Previous PCI | 13 (37.1) | 4 (8.9) | 0 |
| Current CAD (QCA ≥70%) | 35 (100) | 0 | 0 |
| 1 Vessel | 22 (62.9) | 0 | 0 |
| 2 Vessels | 9 (25.7) | 0 | 0 |
| 3 Vessels | 4 (11.4) | 0 | 0 |
Values are n (%) or mean ± SD.
ACE = angiotensin-converting enzyme; CAD = coronary artery disease; HDL = high-density lipoprotein; LDL = low-density lipoprotein; PCI = percutaneous coronary interventions; QCA = quantitative coronary angiography.