TABLE 1.
Reference standards
Reference test that must be positive to classify subject as infected (otherwise subject is classified as uninfected) |
Test evaluated |
---|---|
Standards not using discrepant analysis | |
Single-test standards | |
Culture+ | LCR and PCR |
LCR+ | Culture and PCR |
PCR+ | Culture and LCR |
Both+ standards | |
Culture+ and LCR+ | PCR |
Culture+ and PCR+ | LCR |
LCR+ and PCR+ | Culture |
Either+ standards | |
Culture+ or LCR+ | PCR |
Culture+ or PCR+ | LCR |
LCR+ or PCR+ | Culture |
Either+/TMA+ standards | |
Culture+, LCR+, or TMA+ | PCR |
Culture+, PCR+, or TMA+ | LCR |
LCR+, PCR+, or TMA+ | Culture |
Standards using discrepant analysis | |
DA-Culture standard: culture+ or LCR+ and PCR+ | Culture, LCR, and PCR |
DA-Any 2+ standard: Culture+ and LCR+, culture+ and PCR+, or LCR+ and PCR+ | Culture, LCR, and PCR |
DA-TMA standards | |
Culture+ or LCR+, or PCR+ and TMA+ | PCR |
Culture+ or PCR+, or LCR+ and TMA+ | LCR |
LCR+ or PCR+, or culture+ and TMA+ | Culture |