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. 2021 Dec 31;21(1):e13538. doi: 10.1111/acel.13538

FIGURE 1.

FIGURE 1

Timeline of advances in rejuvenation research. Several potential rejuvenation therapies that fall into the three major categories are listed in chronological order. Treatments marked in red show a reversal in biological age as assessed by epigenetic clocks. Additional studies not shown on this timeline are described in Table 1. RF, reprogramming factor