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. 2021 Dec 2;164(1):61–77. doi: 10.1007/s00701-021-05054-0

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Summary of symptoms at presentation. A Summary of patient-specific demographic (top), presentation (middle) and outcome (bottom) features. Each patient is shown as a vertical segment along the x axis. Different features are labelled according to the legend. B Proportion of patients by presenting symptom. C Proportion of patients by number of symptoms at presentation. Of note, 5 patients reportedly had no symptoms at presentation. These are briefly described below. D Distribution of associated symptoms in patients presenting with only 1, 2 or 3 symptoms (from left to right, respectively). The distribution of patients presenting with 4 and 5 + symptoms is shown in Supplementary Fig. 5. E Co-occurrence of clinical characteristics at presentation. Data represented as correlation matrix, where the correlation coefficient (Pearson) between characteristics X and Y is shown on a colour scale ranging from blue (positive correlation) to red (negative correlation). White corresponds to a correlation coefficient of 0. Statistically significant correlations are marked by one or more ‘*’, according to a conventional notation of statistical significance (* < 0.05; ** < 0.01, *** < 0.005). *5 patients had no reported symptoms at presentation: (1) No symptom reported, surgical indication: ‘progressing cyst size’. (2) 4 years old asymptomatic, surgical indication: ‘cyst with partial solid enhancement’; (3) 54 years old asymptomatic, surgical indication: ‘solid posterior part of the cyst’; (4) 29 years old, no symptoms reported, surgical indication: ‘large cyst unspecified symptoms’; (5) 16 years old, presentation data not available, indication for surgery: not available. The figure is available in colour online. Size_mm_12: cyst size > 12 mm; Visual_sx, visual symptoms; Neurology_NOS, neurology not otherwise specified; Resection_extent, cyst resection, as opposed to cyst fenestration; Sleep, sleep disturbances; Pysch_depression, psychiatric symptoms of depression; Other_sx, any of the following symptoms: ‘Cognitive’, ‘Transient_LoC’, ‘Sleep’, ‘Pysch_depression’, ‘Seizure’, ‘Neurology_NOS’, ‘Fatigue’; LoC, loss of consciousness; HA, headache; V, visual symptoms; NV, nausea and vomiting; DV, dizziness and vertigo; P, psychiatric symptoms; F, fatigue; G, gait abnormalities; N, neurology not otherwise specified; Seiz, seizures; S, sleep disturbances