Table 2. Suggested regimen approach for vitamin D supplementation in patients with prostate cancer under androgen deprivation therapy.

Vitamin D deficiency (25-hydroxyvitamin D <20 ng/mL)
	• Cholecalciferol 50,000 IU weekly for 8 weeks
	• Calcifediol 16,000 IU (0.266 mg) weekly for 4 weeks
	• This regimen should be followed by the maintenance dose.
Vitamin D insufficiency (25-hydroxyvitamin D=20–30 ng/mL)
	• Cholecalciferol 25,000–50,000 IU weekly for 6 weeks
	• Calcifediol 16,000 IU (0.266 mg) weekly for 3 weeks
	• This regimen should be followed by the maintenance dose.
Maintenance dose of vitamin D supplementation in patients with optimal 25-hydroxyvitamin D levels (30–50 ng/mL)
	• Cholecalciferol 25,000–50,000 IU monthly (800–1,666 IU per day)
	• Calcifediol 16,000 IU (0.266 mg) every 3–4 weeks