Table 1. Studies investigating the relationship between T1DM, T2DM, PreDM, and PE in men.

Study	Year	Definition of PE	Disorder	PE prevalence	Results
El-Sakka [38]	2003	The persistent or recurrent inability to voluntarily delay ejaculation either upon or shortly after penetration or with minimal sexual stimulation.	T2DM	50 years old ↓ 32.4% 50 years old ↑ 67.6%	Long diabetes duration, poor glycemic control, and the presence of ED increased risk of PE
Corona et al [45]	2004	PE was defined as ejaculation within 1 minute of vaginal intromission (as reported by the patient)	PreDM, T2DM	28.4%	There was no relationship between PE and FBS.
Basile Fasolo et al [40]	2005	DMS-IV	T2DM	21.2%	Decreased PE in those treated for T2DM
Owiredu et al [36]	2011	GRISS	T2DM	56.6%	Testosterone levels were negatively correlated with FBS, HbA1C, short IELT, weight, and WC.
Bellastella et al [42]	2015	PEDT	T1DM	24%	PE prevalence in T1DM same as control. PEDT score was strongly associated with LBGI
Majzoub et al [39]	2016	AIPE	T2DM	60.2%	LPE and APE were higher, and mean IELT was lower, in patients with T2DM compared to controls.
Salama et al [21]	2017	PEDT	PreDM	35.2%	Higher PEDT, higher FBS
Bolat et al [46]	2017	PEDT	PreDM	-	PEDT score higher, IELT score lower in PE

PE: premature ejaculation, T2DM: type 2 diabetes mellitus, ED: erectile dysfunction, PreDM: prediabetes mellitus, FBS: fasting blood sugar, DMS-IV: Diagnostic and Statistical Manual of Mental Disorders-IV, GRISS: Golombok Rust Inventory of Sexual Satisfaction, HbA1c: glycated hemoglobin, IELT: intravaginal ejaculatory delay time, WC: waist circumference, T1DM: type 1 diabetes mellitus, PEDT: premature ejaculation diagnostic tool, LBGI: low blood glucose indexes, AIPE: Arabic Index for Premature Ejaculation, LPE: lifetime pemature ejaculation, APE: acquired premature ejaculation, -: not available.