Table 1.

Demographics, comorbidities, orotracheal intubation timing and ICU admission severity

	All (n = 139)	TIB (n = 75)	No TIB (n = 64)	p	VEP (n = 108)	No VEP (n = 31)	p
Demographics and comorbidities
Age—yr (IQR)	66 (57–74)	67 (59–74)	64 (57–74)	0.404	68 (59–74)	63 (56–70)	0.115
Sex—male—no (%)	104 (74.8%)	54 (72%)	50 (78.1%)	0.407	80 (74.1%)	24 (77.4%)	0.705
BMI—median (IQR)	28 (25–32)	28 (25–31)	29 (26–33)	0.033	28 (25–31)	28 (25–33)	0.838
Hypertension—no (%)	86 (61.9%)	41 (54.7%)	45 (70.3%)	0.058	65 (60.2%)	21 (67.7%)	0.445
Chronic ischemic heart disease—no (%)	12 (8.6%)	5 (6.7%)	7 (10.9%)	0.372	8 (7.4%)	4 (12.9%)
Chronic kidney disease (CKD)				0.567*			0.790*
CKD—not in dialysis—no (%)	7 (5.0%)	2 (3.1%)	5 (6.7%)		6 (5.6%)	1 (3.2%)
CKD—patients in dialysis—no (%)	3 (2.2%)	2 (2.7%)	1 (1.6%)		2 (1.9%)	1 (3.2%)
COPD—no (%)	8 (5.8%)	6 (8.0%)	2 (3.1%)	0.267*	6 (5.6%)	2 (6.5%)	0.852*
COPD—home oxygen therapy/CPAP—no (%)	1 (0.7%)	0 (0%)	1 (1.6%)		1 (0.9%)	0 (0%)
Diabetes—no (%)	36 (25.9%)	18 (24%)	18 (28.1%)	0.580	30 (27.8%)	6 (19.4%)	0.345
ICU admission and orotracheal intubation
Time from hospital admission to ICU admission—d (IQR)	1 (0–2)	1 (1–3)	1 (0–2)	0.004	1 (0–3)	1 (0–2)	0.089
Time from hospital admission to intubation—d (IQR)	1 (0–3)	2 (1–3)	1 (0–2)	0.002	1 (0–3)	1 (0–2)	0.108
SAPS II score	35 (29–43)	35 (29–43)	35 (30–46)	0.488	35 (29–43)	35 (29–46)	0.757
SOFA score at ICU admission	5 (3–7)	5 (3–7)	5 (3–7)	0.790	5 (3–7)	5 (3–7)	0.927

BMI body mass index, CKD chronic kidney disease, COPD chronic obstructive pulmonary disease, ICU intensive care unit, SAPS simplified acute physiology score, SOFA sequential organ failure assessment, IQR interquartile range

Significant p values are reported in bold. *Refers to the p value of the Chi-square test for the whole contingency table for the variable taken into account