Skip to main content
. Author manuscript; available in PMC: 2022 Sep 29.
Published in final edited form as: ACS Appl Mater Interfaces. 2021 Sep 20;13(38):45300–45314. doi: 10.1021/acsami.1c14082

Figure 1. Schematic illustration of core hydrophobicity as a potential Nanoparticle-Associated-Molecular Pattern (NAMP) responsible for activating NLRP3 inflammasome and its proposed mode of action.

Figure 1.

Top part shows the structures of the polymer construct used for the synthesis of supramolecular nanoparticles (sNPs) with sequential core hydrophobicity contributed by octyl hydrophobic moiety (y). The bottom part displays their detailed signaling pathway for NLRP3 inflammasome activation.