TABLE 5.
The effects of hormone replacement therapy on the level of serum uric acid, the serum lipid concentrations, and the carotid intima‐media thickness
| Variables | No HRT (n = 254) | HRT (n = 250) | p value |
|---|---|---|---|
| Age | 73.12 ± 3.65 | 72.67 ± 3.72 | 0.328 |
| BMI, kg/m2 | 24.65 ± 3.29 | 23.07 ± 3.31 | 0.034 |
| SUA, mg/dL | 7.46 ± 2.46 | 6.95 ± 2.43 | 0.041 |
| Percentage of change of plaque score, % | 10.32 ± 4.17 | 7.65 ± 5.31 | 0.028 |
| Change of CIMT, cm | 0.043 ± 0.009 | 0.011 ± 0.006 | 0.047 |
| TC, mg/dL | 232.65 ± 15.37 | 225.42 ± 12.45 | 0.029 |
| TG, mg/dL | 95.78 ± 23.32 | 92.74 ± 20.45 | 0.031 |
| LDL‐C, mg/dL | 105.46 ± 19.76 | 98.42 ± 17.92 | 0.002 |
| HDL‐C, mg/dL | 72.93 ± 21.36 | 83.45 ± 19.65 | 0.003 |
| Use of statin | 46 (23.2%) | 52 (24.3%) | 0.799 |
Abbreviations: BMI, body mass index; CIMT, carotid intima‐media thickness; HDL‐C, high‐density lipoprotein cholesterol; HRT, hormone replacement therapy; LDL‐C, low‐density lipoprotein cholesterol; SUA, serum uric acid; TC, total cholesterol; TG, triglyceride.