Table 1:

Brief, selected overview of the models that have investigated size control in the wing imaginal disc [76,80,81,88,90–92].

Model Type	Contribution
Continuous	The early models incorporating mechanical feedback were continuous models, which are typically used to model the entire wing disc. (Shraiman et al., 2005) approximates cells as a 2D elastic solid and models the effects of mechanical stress resulting from non-uniform local growth rates. (Aegerter-Wilmsen et al., 2007) models growth of the wing disc, which is induced by the combination of morphogens and stretching and inhibited by compression.
Vertex	More detailed vertex models are used to model individual cells, whereas continuous models typically model an entire region of cells. A vertex model incorporating mechanical feedback was developed in (Hufnagel et al., 2007) to investigate uniform growth resulting from a non-uniform morphogen gradient. Later, the vertex model of (Farhadifar et al., 2007) was extended to include mechanical feedback by division rates that depended on cell areas (Aegerter-Wilmsen et al., 2010).
Hybrid	To explain how mechanical feedback could regulate growth rates, (Aegerter-Wilmsen et al., 2010) was extended to include a regulatory network based on known protein interactions as well as hypothetical interactions for the interactions resulting from mechanical stresses (Aegerter-Wilmsen et al., 2010).