Table 5.

Analysis of nucleotide sequence of spike gene

Groups	Sequence names	§ds	†dn	dn/ds	*Pairwise distance
αI	MT049951_MT121216	0.15	0.17	1.13	0.37
	MT049951_MT072864	0.18	0.18	1	0.45
	MT049951_MT040336	0.18	0.18	1	0.45
	MT049951_MT040335	0.18	0.18	1	0.45
	MT049951_MT040334	0.18	0.18	1	0.45
	MT049951_MT040333	0.18	0.18	1	0.45
βII	MT049951_MH687977	1.19	0.69	0.58	0.72
	MT049951_MH687973	1.21	0.69	0.58	0.73
	MT049951_JF792616	1.14	0.65	0.57	0.73
	MT049951_JF792617	1.15	0.65	0.56	0.73
	MT049951_NC-012936	1.15	0.65	0.57	0.73
	MT049951_KM349742	1.17	0.69	0.59	0.74
	MT049951_KF294371	1.10	0.67	0.61	0.75

^§The rate of nucleotide substitution that caused synonym amino acid changes

^†The rate of nucleotide substitution that caused non-synonym amino acid changes

^*Pairwise distance refers to the amount of difference between nucleotide sequences

^αGroup I including SARS-CoV-2 (MT049951) and pangolin-Covs

^βGroup II including SARS-CoV-2 (MT049951) and Rattus Covs