Table 6.

Nucleotide substitution matrix for spike gene

Groups		A	T/U	C	G
αI	A	–	6.69	4.02	7.71
	T/U	6.20	–	14.37	3.80
	C	6.20	23.91	–	3.80
	G	12.59	6.69	4.02	–
βII	A	–	7.57	4.03	9.65
	T/U	6.16	–	11.38	4.64
	C	6.16	21.36	–	4.64
	G	12.80	7.57	4.03	–

Rates of different transition and transversion substitutions are shown in bold and in italics, respectively

^αGroup I including SARS-CoV-2 (MT049951) and pangolin-Covs

^βGroup II including SARS-CoV-2 (MT049951) and Rattus Covs