Table 3.

Predictive value of CHD1 deletion for metastasis-free survival (multivariate cause-specific Cox proportional hazards model, n = 6831, events = 259).

	HR	95% CI	P value
Surgical margin*CHD1			0.030
Negative: CHD1 (del. vs norm.)	2.32	[1.61, 3.33]	<0.001
Positive: CHD1 (del. vs norm.)	1.04	[0.55, 1.95]	0.907
Age [per 10 years]	0.80	[0.65, 0.99]	0.040
pN status			0.060
Nx vs N0	0.72	[0.47, 1.11]	0.138
N + vs N0	1.34	[0.96, 1.87]	0.085
PSA [per 10 units]	1.00	[0.92, 1.08]	0.916
pT stage			0.061
pT3a vs pT2	0.98	[0.68, 1.41]	0.898
pT3b/pT4 vs pT2	1.37	[0.95, 1.98]	0.096
Gleason group			<0.001
3 + 4 vs ≤3 + 3	3.85	[1.54, 9.61]	0.004
4 + 3 vs ≤3 + 3	8.72	[3.42, 22.24]	<0.001
≥4 + 4 vs ≤3 + 3	14.01	[5.27, 37.22]	<0.001
Surgical margin*BCR			0.006
Negative: BCR (yes vs no)	264.27	[36.77, 1899.41]	<0.001
Positive: BCR (yes vs no)	12.85	[5.2, 31.77]	<0.001