Table 1.
Comparison of demographical characteristics and biochemical variables between survivor and non-survivor groups.
| Survivor Covid-19 | Non-survivor Covid-19 | *p-value | ||
|---|---|---|---|---|
| Median (25 th quartile-75th quartile) | Median (25 th quartile-75th quartile) | |||
| Age | 56.00 (40.00–69.00) | 76.00 68.00 – 82.00) | 0.000 | |
| SexMale n(%)Female n(%) | 2228 (51.1)2136 (48.9) | 143 (61.4)90 (38.6) | 0.000 | |
| Parameters | Reference range | |||
| ALT (pre) U/L | 0–35 | 25.00 (16.00–42.00) | 21.00 (14.00–34.00) | 0.000 |
| ALT (post) U/L | 32.00 (19.00–64.00) | 24.00 (16.00–47.00) | 0.004 | |
| AST (pre) U/L | 0–50 | 26.00 (20.00–37.00) | 30.00 (20.00–47.00) | 0.002 |
| AST (post) U/L | 27.50 (21.00–41.00) | 32.00 (22.00–56.00) | 0.064 | |
| Albumin (pre) μmol/L | 527–782 | 582.30 (516.01–651.52) | 544.84 (476.83–605.63) | 0.000 |
| Albumin (post) μmol/L | 503.31 (454.41–586.82) | 455.91 (386.70–556.72) | 0.001 | |
| Alkaline Phosphatase (pre) μmol/s.L | 0.5–2.0 | 1.25 (1.03–1.57) | 1.42 1.10–3.13) | 0.000 |
| Alkaline Phosphatase (post) μmol/s.L | 1.09 (1.09–1.7) | 1.55 (1.20–2.00) | 0.020 | |
| Amylase (pre) μmol/s.L | 0.47–1.67 | 1.13 (0.85–1.50) | 1.12 (0.78–1.48) | 0.685 |
| Amylase (post) μmol/s.L | 1.46 (1.00–1.78) | 1.13 (1.13–1.53) | 0.058 | |
| CK - MB (pre) u/L | 0–24 | 15.70 (12.40–21.60) | 22.65 (15.60–31.40) | 0.000 |
| CK - MB (post) u/L | 16.90 (12.70–21.10) | 21.40 (16.10–32.00) | 0.000 | |
| Direct Bilirubin (pre) μmol/L | 0–3.4 | 1.88 (1.37–2.56) | 2.39 (1.54–4.10) | 0.000 |
| Direct Bilirubin (post) μmol/L | 1.88 (1.37 – 2.56) | 2.91 (1.88–4.61) | 0.000 | |
| GGT (pre) μmol/s.L | 0–0.63 | 0.51(0.30–0.94) | 0.55 (0.32–1.18) | 0.139 |
| GGT (post) μmol/s.L | 0.78 (0.42–1.32) | 0.77 (0.37–2.01) | 0.779 | |
| Glucose (pre) mmol/L | 4.11–5.55 | 5.99 (5.16–8.10) | 7.72 (6.22–10.77) | 0.000 |
| Glucose (post) mmol/L | 6.27 (5.16–10.05) | 8.21(6.27–13.82) | 0.000 | |
| HDL Cholesterol (pre) mmol/L | 1.03–1.55 | 0.35 (27.00–0.70) | 0.88 (0.80–1.24) | 0.234 |
| HDL Cholesterol (post) mmol/L | 0.93 (0.72 – 1.11) | 0.82 (0.72–1.03) | 0.427 | |
| Cholesterol (pre) mmol/L | 0–5.17 | 4.19 (3.49–5.04) | 4.26 (3.62–5.66) | 0.432 |
| Cholesterol (post) mmol/L | 4.60 (3.72–5.61) | 4.32 (3.49–5.35) | 0.370 | |
| Creatinine (pre) μmol/L | 74.26–110.50 | 80.44 (68.95–92.82) | 96.35 (75.14–133.48) | 0.000 |
| Creatinine (post) μmol/L | 83.09 (68.95–99.89) | 103.43 (82.21–152.93) | 0.000 | |
| Creatine Kinase (pre) u/L | 0–145 | 71.00 (44.00–106.00) | 101.00 (59.00–237.00) | 0.000 |
| Creatine Kinase (post) u/L | 44.00 (31.00–91.50) | 91.00 (50.00–171.00) | 0.000 | |
| LDH (pre) u/L | 0–248 | 233.00 (193.00–292.00) | 289.00 (223.00–367.00) | 0.000 |
| LDH (post) u/L | 264.00 (217.00–332.00) | 338.50 (255.00–484.50) | 0.000 | |
| Total Bilirubin (pre) μmol/L | 5.13–20.52 | 8.04 (5.98–10.94) | 9.74 (6.67–14.19) | 0.000 |
| Total Bilirubin (post) μmol/L | 8.38 (6.15–11.45) | 10.60 (7.18–15.73) | 0.003 | |
| Total Protein (pre) g/L | 66–83 | 68.10 (63.40–73.45) | 66.33 (59.71–70.24) | 0.000 |
| Total Protein (post) g/L | 64.60 (57.25–69.95) | 61.35 (54.70–68.50) | 0.071 | |
| Triglyceride (pre) mmol/L | 0–1.69 | 1.49 (1.08–2.10) | 1.26 (1.04–2.05) | 0.558 |
| Triglyceride (post) mmol/L | 1.71 (1.36–2.41) | 1.62 (0.84–2.89) | 0.510 | |
| eGFR (pre) | 85.10 (66.33–99.36) | 61.08 (40.86–83.83) | 0.000 | |
| eGFR (post) | 77.44 (56.04–92.94) | 55.48 (34.34–76.59) | 0.000 | |
| Urea (pre) mmol/L | 2.83–7.16 | 5.33 (3.99–7.61) | 8.88 (6.46–13.32) | 0.000 |
| Urea (post) mmol/L | 6.99 (4.99–10.32) | 11.57 (7.49–22.81) | 0.000 | |
| Uric acid (pre) mmol/L | 0.21–0.43 | 0.30 (0.24–0.39) | 0.40 (0.29–0.51) | 0.000 |
| Uric acid (post) mmol/L | 0.28 (0.20–0.38) | 0.33 (0.27–0.40) | 0.141 |
ALT: alanine aminotransaminase; AST: aspartate aminotransferase; CK-MB: creatine kinase myocardial band; GGT: Gamma Glutamyl Transferase enzyme; LDH: lactate dehydrogenase; eGFR: estimated glomerular filtration rate; IQR: interquartile range; The p values indicate the comparison of the survivor and non-survivor groups in pre-post measurements and they are bold when p < 0.05.