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. 2022 Jan 17;105:108542. doi: 10.1016/j.intimp.2022.108542

Table 3.

Comparison of inflammatory, cardiac and coagulation variables between survivor and non-survivor groups.

survivor Covid-19 non-survivor Covid-19 *p-value
Median (25 th quartile-75th quartile) Median (25 th quartile-75th quartile)
Parameters Reference range
CRP (pre) mg/L 0–5 6.76 (3.02–25.20) 63.91 (17.10–72.90) 0.000
CRP (post) mg/L 6.42 (3.02–41.00) 97.61 (37.70–146.00) 0.000
D-dimer (pre) μg/L 80–583 441.00 (252.00–843.95) 1390.00 (599.36 – 1992.00) 0.000
D-dimer (post) μg/L 524.55 (232.00–1249.63) 2214.19 (852.81–4460.00) 0.000
Ferritin (pre) μg/L Male: 22–322 Female: 10–291 125.95 (47.10–317.50) 379.38 (282.50–395.00) 0.000
Ferritin (post) μg/L 224.30 (75.90–436.40) 527.18 (216.50–1650.00) 0.000
Fibrinogen (pre) g/L 18–145 3.211 (2.878–3.649) 3.50 (3.50–3.50) 0.000
Fibrinogen (post) g/L 3.24 (2.81–3.73) 3.50 (3.50 – 3.50) 0.002
INR (pre) 0.6–1.2 1.10 (1.04–1.17) 1.25 (1.20–1.44) 0.000
INR (post) 1.10 (1.03–1.16) 1.20 (1.20–1.20) 0.000
PT (pre) Sec 10.1–15.9 13.10 (12.40–13.90) 14.83 (14.20–16.90) 0.000
PT (post) Sec 13.10 (12.30–13.80) 14.20 (14.20–14.20) 0.000
Procalcitonin (pre) μg/L < 0.15 0.12 (0.12–0.12) 2.53 (2.53–3.00) 0.000
Procalcitonin (post) μg/L 0.12 (0.12 – 0.19) 3.46 (0.17–4.00) 0.000
ESR (pre) mm/hr 0–20 17.00 (70.00–38.00) 47.05 (20.00–49.00) 0.000
ESR (post) mm/hr 19.00 (8.00–55.50) 52.36 (15.00–79.00) 0.000
Troponin (pre) ng/L 10–23 17.00 (10.00–22.51) 57.00 (10.00–112.75) 0.000
Troponin (post) ng/L 10.00 (10.00–10.00) 112.00 (10.00–10.00) 0.000
aPTT (pre) Sec 22–45 35.34 (29.20–37.05) 31.00 (30.00–32.00) 0.000
aPTT (post) Sec 33.30 (28.10–38.80) 32.00 (32.00–32.20) 0.047

CRP: C-reactive protein; INR: international normalized ratio; PT: prothrombin time; ESR: erythrocyte sedimentation rate; aPTT: activated partial prothrombin time; IQR: interquartile range; The p values indicate the comparison of the Survivor and non-Survivor groups in pre-post measurements and they are bold when p < 0.05.