Table 1.
Summary of the in silico toxicity of the chemical compounds with anti-theilerial activity.
| Compounda | Activity against other infectious microorganisma |
In silico toxicity featuresb |
||||
|---|---|---|---|---|---|---|
| Acute cytotoxicity (fathead minnow) (mg/liter) | Carcinogenicity (Rodent) | Mutagenicity (Salmonella typhimurium) | Blood brain barrier penetration (Human) | Maximum recommended daily dose (Human) (mg/kg body weight/day) | ||
| MMV000062 | Trypanosoma | 15.1 | non-carcinogenic | non-mutagenic | penetrating | data unavailable |
| MMV560185 | Plasmodium | 13 | carcinogenic | mutagenic | penetrating | 10 |