Table 3.
Comparisons of the covariates after propensity score matching.
| Variables |
Control group (n = 652) |
UFH group (n = 652) |
SMD |
|---|---|---|---|
| Age, years | 65.0 (51.0, 76.0) | 65.0 (51.0, 77.2) | 0.017 |
| Male | 381 (58.4%) | 385 (59.0%) | 0.016 |
| Laboratory tests | |||
| WBC count, (103/μL) | 11.9 (8.4, 16.9) | 11.9 (8.3, 16.0) | 0.033 |
| Hemoglobin, (g/dL) | 10.5 (9.4, 11.8) | 10.6 (9.4, 11.7) | 0.021 |
| Platelet, (103/μL) | 159.5 (112.0, 259.0) | 172.0 (127.0, 262.0) | 0.012 |
| INR | 1.4 (1.4, 1.7) | 1.4 (1.4, 1.6) | 0.004 |
| PTT, (s) | 35.7 (29.8, 49.6) | 36.4 (29.8, 50.9) | 0.004 |
| Albumin, (g/dL) | 2.6 (2.4, 2.9) | 2.6 (2.4, 2.9) | 0.029 |
| Bilirubin, (mg/dL) | 1.1 (0.5, 1.9) | 0.9 (0.5, 1.9) | 0.010 |
| Scr, (mg/dL) | 1.1 (0.8, 1.8) | 1.1 (0.8, 1.8) | 0.029 |
| pH | 7.37 (7.29, 7.43) | 7.35 (7.26, 7.42) | 0.007 |
| PO2, (mmHg) | 138.0 (81.0, 238.2) | 142.5 (86.0, 221.5) | 0.023 |
| PCO2, (mmHg) | 42.0 (35.0, 46.0) | 42.0 (35.0, 48.0) | 0.012 |
| Lactate, (mmol/L) | 2.9 (1.7, 2.9) | 2.5 (1.4, 3.0) | 0.006 |
| Anion gap, (mmol/L) | 16.0 (13.0, 19.0) | 16.0 (14.0, 19.0) | 0.024 |
| Bicarbonate, (mmol/L) | 21.0 (17.0, 24.0) | 21.0 (17.0, 24.0) | 0.004 |
| Sodium, (mmol/L) | 141.0 (138.0, 144.0) | 141.0 (138.0, 144.0) | 0.013 |
| Potassium, (mmol/L) | 4.5 (4.1, 5.1) | 4.5 (4.2, 5.1) | 0.022 |
| Chloride, (mmol/L) | 103.0 (99.0, 107.0) | 103.0 (99.0, 107.0) | 0.018 |
| Vital signs | |||
| Temperature (°C) | 37.1 (36.6, 37.6) | 37.0 (36.6, 37.5) | 0.023 |
| MAP, (mmHg) | 75.7 (69.1, 83.1) | 75.9 (70.6, 83.0) | 0.049 |
| Heart rate, (min, −1) | 90.6 (78.9, 102.8) | 90.1 (78.0, 101.9) | 0.014 |
| Respiratory rate, (min, −1) | 19.6 (16.2, 22.9) | 19.4 (17.0, 22.7) | 0.013 |
| Comorbidities, n (%) | |||
| Hypertension | 225 (34.5%) | 227 (34.8%) | 0.013 |
| DM | 173 (26.5%) | 187 (28.7%) | 0.020 |
| CHD | 108 (16.6%) | 113 (17.3%) | 0.004 |
| COPD | 12 (1.8%) | 12 (1.8%) | 0.000 |
| CKD | 68 (10.4%) | 77 (11.8%) | 0.010 |
| Source of infection, n (%) | |||
| Lung | 441 (67.6%) | 436 (66.9%) | 0.000 |
| Abdomen | 66 (10.1%) | 67 (10.3%) | 0.031 |
| Urine | 261 (40.0%) | 267 (41.0%) | 0.013 |
| Soft tissue | 32 (4.9%) | 29 (4.4%) | 0.025 |
| Central nervous system | 8 (1.2%) | 6 (0.9%) | 0.014 |
| Treatment | |||
| Vasopressor | 234 (3.6%) | 244 (3.7%) | 0.032 |
| Mechanical ventilation | 506 (77.6%) | 506 (77.6%) | 0.000 |
| RRT | 30 (4.6%) | 29 (4.4%) | 0.007 |
| Severity scales | |||
| SOFA | 6 (4, 9) | 6 (4, 9) | 0.006 |
| SAPSII | 42 (34, 54) | 43 (33, 52) | 0.002 |
Values were shown as median (interquartile range) unless otherwise indicated.
WBC, white blood cell; INR, international normalized ratio; PTT, partial thromboplastin time; Scr, serum creatitine; PO2, partial pressure of oxygen; PCO2, partial pressure of carbon dioxide; MAP, mean arterial pressure; DM, diabetes mellitus; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; CKD, chronic renal disease; RRT, renal replacement therapy; SMD, standardized mean difference; SOFA, Sequential Organ Failure Assessment; SAPSII, Simplified Acute Physiology Score II.