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. 2022 Jan 3;8:772700. doi: 10.3389/fnut.2021.772700

Table 2.

Odds ratios (ORs) and 95% CIs for the association between alcohol consumption and coronavirus disease 2019 (COVID-19) risk, separated by frequency of alcohol intake.

Variables (a) Frequency of alcohol intake, OR (95% Cl)
Once a month-twice/week p ≥ 3 times/week p
Alcohol consumption, dosage
Never drinker, previous-drinkers or special occasions only Reference Reference
Within guidelines 1.01 (0.92–1.11) 0.8 0.96 (0.62–1.49) 0.9
Above guidelines 1.06 (0.91–1.24) 0.4 1.00 (0.64–1.54) 1.0
Double above the guidelines or more 1.07 (0.85–1.35) 0.6 1.04 (0.67–1.62) 0.9
Red wine drinkers
Nondrinkers Reference Reference
1–2 glasses/week 0.89 (0.82–0.97) 0.005 0.88 (0.81–0.97) 0.006
3–4 glasses/week 0.90 (0.82–1.00) 0.044 0.90 (0.83–0.99) 0.023
≥ 5 glasses/week 0.82 (0.71–0.93) 0.003 0.83 (0.77–0.89) <0.001
White wine and champagne drinkers
Non-drinkers Reference Reference
1–2 glasses/week 0.95 (0.88–1.02) 0.2 0.93 (0.86–1.01) 0.069
3–4 glasses/week 0.94 (0.84–1.05) 0.3 0.91 (0.83–0.99) 0.037
≥ 5 glasses/week 1.06 (0.92–1.22) 0.4 0.91 (0.85–0.99) 0.019
Beer and cider drinkers
Non-drinkers Reference Reference
1–2 glasses/week 1.11 (1.03–1.21) 0.01 1.06 (0.98–1.15) 0.2
3–4 glasses/week 1.24 (1.11–1.39) <0.001 1.18 (1.07–1.31) 0.001
≥ 5 glasses/week 1.34 (1.17–1.53) <0.001 1.31 (1.20–1.44) <0.001
Spirits drinkers
Non-drinkers Reference Reference
1–2 glasses/week 0.99 (0.91–1.07) 0.8 0.97 (0.90–1.04) 0.4
3–4 glasses/week 1.09 (0.97–1.23) 0.1 1.02 (0.92–1.12) 0.7
≥ 5 glasses/week 1.11 (0.97–1.26) 0.1 1.09 (1.01–1.17) 0.033
Fortified wine drinkers
Non-drinkers Reference Reference
1–2 glasses/week 0.80 (0.69–0.92) 0.002 0.93 (0.83–1.04) 0.2
3–4 glasses/week 0.94 (0.65–1.35) 0.7 0.94 (0.74–1.19) 0.6
≥ 5 glasses/week 1.15 (0.70–1.89) 0.6 1.07 (0.86–1.34) 0.5

Logistic regression analysis adjusted for age, sex, education, ethnicity, employment, body mass index (BMI), overall health rating, Townsend, usually walking pace, cerebrovascular diseases, hypertension, cardiovascular diseases, diabetes, respiratory disease, cancer, amount of weekly intake level of alcohol consumption, red wine, champagne plus white wine, beer and cider, spirits, and fortified wine.