Table4.
Results of multiple regression analysis with MMSE score as the dependent variable
| Task | Hand | Independent variables | Standardized coefficients β |
95% CI | p-value | |
|---|---|---|---|---|---|---|
| lower | upper | |||||
| Dominant hand task | Right | SD of distance rate of velocity peak in extending movements | –0.442 | –169.469 | –54.291 | 0.000 |
| R2 | 0.2 | |||||
| Non-dominant hand task | Left | SD of contact duration | –0.449 | –188.290 | –63.294 | 0.000 |
| Avg. of distance rate of velocity peak in extending movement | –0.243 | –39.909 | –1.697 | 0.033 | ||
| R2 | 0.28 | |||||
| In-phase task | Right | SD of distance rate of velocity peak in extending movements | –0.466 | –152.075 | –53.079 | 0.000 |
| R2 | 0.22 | |||||
| Left | SD of contact duration | –0.320 | –224.048 | –34.450 | 0.008 | |
| Slope of approximate line of local max. points | –0.237 | –2.334 | –0.011 | 0.048 | ||
| R2 | 0.19 | |||||
| Anti-phase task | Right | SD of inter-tapping interval | –0.319 | –37.371 | –5.253 | 0.01 |
| R2 | 0.1 | |||||
| Left | SD of inter-tapping interval | –0.323 | –44.477 | –6.513 | 0.009 | |
| R2 | 0.104 | |||||
MMSE: Mini-Mental State Examination; CI: confidence interval; R2: coefficient of determination; Max: Maximum; Ave: Average; SD: Standard deviation
There was no significant difference in the other parameters.
* SD of distance rate of velocity peak in extending movement (No. 17): variability in the values calculated as the ratio of the position at the maximum velocity of the finger extension to the amplitude.
* SD of contact duration (No. 25): variability of the duration while two fingers (the thumb and index finger) contact each other.
* SD of inter-tapping interval (No. 29): variability of inter-tapping interval (the difference in time of the minimum points of two consecutive tapping movements). The larger this value, the more inconsistent the inter-tapping interval.
* Average distance rate of velocity peak in extending movement (No. 14): The mean value calculated as the ratio to the amplitude of the distance at the maximum velocity during finger extension.
* Slope of approximate line of local max. points (No. 5): The slope of the linear regression of the relationship between the maximum points (the maximum point per tapping movement) and the duration.