Table 4.

Estimates of the absolute number and % of viraemic HCV individuals in Italy according to fibrosis stage, route of transmission and macro area

Macroarea	Transmission route	Fibrosis stage	Absolute number			Prevalence (%)
			Number	Lower 95% CI	Upper 95% CI	Mean	Lower 95% CI	Upper 95% CI
North	GS + transfusion	F0–F3	3318	2591	4118	0.01	0.01	0.01
		F4	6817	5211	8384	0.02	0.02	0.03
	PWID	F0–F3	64,922	51,853	79,217	0.23	0.18	0.28
		F4	15,399	11,393	19,517	0.05	0.04	0.07
	Sex	F0–F3	18,722	14,870	22,705	0.07	0.05	0.08
		F4	1156	816	1482	< 0.01	< 0.01	0.01
	Tattoo	F0–F3	38,761	30,970	47,218	0.14	0.11	0.17
		F4	4260	3026	5614	0.02	0.01	0.02
	Vertical	F0–F3	652	508	827	< 0.01	< 0.01	< 0.01
		F4	367	271	474	< 0.01	< 0.01	< 0.01
Central	GS + transfusion	F0–F3	4713	3681	5780	0.04	0.03	0.05
		F4	14,882	11,763	18,069	0.12	0.1	0.15
	PWID	F0–F3	36,674	29,263	44,609	0.31	0.24	0.37
		F4	14,781	11,568	18,194	0.12	0.1	0.15
	Sex	F0–F3	9796	7819	11,863	0.08	0.07	0.1
		F4	922	690	1156	0.01	0.01	0.01
	Tattoo	F0–F3	20,894	16,638	25,354	0.17	0.14	0.21
		F4	3687	2793	4645	0.03	0.02	0.04
	Vertical	F0–F3	376	297	462	< 0.01	< 0.01	< 0.01
		F4	365	291	449	< 0.01	< 0.01	< 0.01
South	GS + transfusion	F0–F3	5423	4242	6733	0.04	0.03	0.05
		F4	17,035	13,367	20,767	0.12	0.1	0.15
	PWID	F0–F3	34,432	27,465	41,917	0.25	0.2	0.3
		F4	12,548	9707	15,594	0.09	0.07	0.11
	Sex	F0–F3	9444	7523	11,516	0.07	0.05	0.08
		F4	799	589	1003	0.01	< 0.01	0.01
	Tattoo	F0–F3	19,834	15,787	24,109	0.14	0.11	0.17
		F4	3064	2281	3925	0.02	0.02	0.03
	Vertical	F0–F3	407	316	512	< 0.01	< 0.01	< 0.01
		F4	354	281	439	< 0.01	< 0.01	< 0.01
Isles	GS + transfusion	F0–F3	1958	1525	2404	0.03	0.02	0.04
		F4	5861	4626	7192	0.09	0.07	0.11
	PWID	F0–F3	15,268	12,147	18,505	0.23	0.19	0.28
		F4	4787	3722	5964	0.07	0.06	0.09
	Sex	F0–F3	4628	3681	5632	0.07	0.06	0.09
		F4	372	274	484	0.01	< 0.01	0.01
	Tattoo	F0–F3	9748	7782	11,851	0.15	0.12	0.18
		F4	1403	1037	1843	0.02	0.02	0.03
	Vertical	F0–F3	201	155	253	< 0.01	< 0.01	< 0.01
		F4	155	111	202	< 0.01	< 0.01	< 0.01

Fibrosis stages: F0–F3 = asymptomatic; undiagnosed/unlinked to care and F4 = symptomatic; potentially linked to care and cure

CI confidence intervals, GS glass syringe, HCV hepatitis C virus, PWID people who inject drugs