Table 2.

The efficacy in chemotherapy and endostar combined with chemotherapy.

Efficacy at the 12th week
	Chemotherapy	endostar combined with chemotherapy	p value
Patients number	72	84
CR	0/72, 0%	5/84, 5.9%	NA
PR	13/72, 18.1%	29/84, 34.5%	0.021
SD	40/72, 55.6%	33/84, 39.3%	0.042
PD	19/72, 26.4%	17/84, 20.2%	0.363
ORR	18.1% (13/72)	40.5% (34/84)	0.002
DCR	73.6% (53/72)	79.8% (67/84)	0.363
Efficacy at the end of follow-up
	Chemotherapy	endostar combined with chemotherapy
Patients number	72	84
CR	0/72, 0%	4/84, 4.8%	NA
PR	1/72, 1.4%	5/84, 5.9%	0.289
SD	3/72, 4.2%	13/84, 15.5%	0.02
PD	68/72, 94.4%	62/84, 73.8%	0.001
ORR	1.4% (1/72)	10.7% (9/84)	0.041
DCR	5.6% (4/72)	26.2% (22/84)	0.001
mPFS (month)	6.87	10.42	0.003
mOS (month)	23.56	26.84	0.481

N/A, Not Available.