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. 2021 Dec 8;81(2):278–288. doi: 10.1136/annrheumdis-2021-221267

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Case–control comparison of the crAss-like phage abundance. (A) Case–control comparison of the crAss-like phage abundance for RA (left), SLE (middle) and MS (right). Boxplots indicate the median values (centre lines) and IQRs (box edges), with the whiskers extending to the most extreme points within the range between (lower quantile−(1.5×IQR)) and (upper quantile+(1.5×IQR)). (B) Case–control comparison of the crAss-like phage abundance for autoimmunity. Boxplots indicate the median values (centre lines) and IQRs (box edges), with the whiskers extending to the most extreme points within the range between (lower quantile−(1.5×IQR)) and (upper quantile+(1.5×IQR)). HC, healthy control; MS, multiple sclerosis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus.