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. 2021 Nov 26;71(2):238–253. doi: 10.1136/gutjnl-2021-325630

Table 4.

Bismuth and PPI containing quadruple therapies currently recommended for Helicobacter pylori eradication by the ‘Fifth National Consensus Report on the Management of Helicobacter pylori Infection’1

Regimens Antibiotic 1 Antibiotic 2
1 Amoxicillin 1000 mg, two times a day Clarithromycin 500 mg, two times a day
2 Amoxicillin 1000 mg, two times a day Levofloxacin 500 mg, one time a day; or 200 mg, two times a day
3 Amoxicillin 1000 mg, two times a day Furazolidone 100 mg, two times a day
4 Tetracycline 500 mg, three or four times a day Metronidazole 400 mg, three or four times a day
5 Tetracycline 500 mg, three or four times a day Furazolidone 100 mg, two times a day
6 Amoxicillin 1000 mg, two times a day Metronidazole 400 mg, three or four times a day
7 Amoxicillin 1000 mg, two times a day Tetracycline 500 mg, three or four times a day

Standard dose isPPI+bismuth compound (two times/day, orally half an hour before meals)+two antibiotics (orally after meals). The standard doses of PPIs are esomeprazole 20 mg, rabeprazole 10 mg (or 20 mg), omeprazole 20 mg, lansoprazole 30 mg, pantoprazole 40 mg and prazole 5 mg. The standard dose of bismuth is 220 mg of potassium bismuth citrate (the standard dose of bismuth pectin is to be determined).1

PPI, proton pump inhibitor.