Table 5.

Accuracy of current commonly used Helicobacter pylori diagnosis methods

H. pylori diagnosis tests	Sensitivity	Specificity	Positive predictive value	Negative predictive value
Non-invasive tests
13C-UBT135 138 161	90.0%–96.0%	94%–98.0%	97.4%–99.2%	90.8%–91.2%
14C-UBT135 136 148 162	96%–97.3%	91%–97.0%	93.31%–96.8%	94.3%–97.6%
Serum anti-H. pylori IgG antibody test142–144  Serum anti-H. pylori protein array UreB/CagA/VacA145	72.7%–90.0% 93.4%/95.4%/96.04%	68.4%–100.0% 94.8%/94.4%/97.5%	66.7%–100.0% N/A	74.3%–83.3% N/A
HpSA ELISA test133 146–148	73.9%–95.0%	86.8%–100.0%	85%–100.0%	76.5%–92.0%
Invasive tests
RUT148 149 161	85.0%–99.0%	92.4%–94.1%	90.5%–97.4%	86.5%–99.2%
Histology138 150 151 161	83%–95.5%	95.4%–100.0%	94.6%–100.0%	88.6%–97.0%
Culture148 150 152	67.9%–96.0%	79.4%–100.0%	88.7%–100.0%	50.9%–95.0%

HpSA, Helicobacter pylori stool antigen test; N/A, not available; RUT, rapid urease test; UBT, urea breath test.