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. 2021 Dec 22;298(1):101521. doi: 10.1016/j.jbc.2021.101521

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Translational repression of CD200R1 in microglia.A, the plausible relationship between miR-129-5p and CD200R1 deduced from the results of the study is shown here in an IPA generated network with the new link shown in pink. The symbols are indicated in the legend. Significantly downregulated genes are in green, upregulated are in red. Solid and dotted lines indicate direct and indirect interactions, respectively. B, proposed pathway of posttranscriptional regulation of CD200R1 and its impact on neuroinflammation.