Table 3.

Enhancing Nutrition and Antenatal Infection Treatment study outcomes

PRIMARY OUTCOMES
P1. Newborn weight	Weight of the unclothed infant measured at <72 hours of life.
P2. Newborn length	Infant length measured at <72 hours of life.
SECONDARY OUTCOMES
S1. Gestational age	Gestational age determined by enrolment ultrasound, CRL used if <95 mm (INTERGROWTH 21st), then BPD/FL (WHO Kiserud) used if CRL >95 mm or missing.
S2a. Proportion of pregnancies resulting in delivery at <37 weeks gestation	Numerator: number of pregnancies resulting in spontaneous termination of pregnancy at <37 weeks gestation (including preterm live birth or fetal loss (spontaneous pregnancy loss, not due to induced abortion)). Denominator: All pregnancy outcomes.
S2b. Preterm live birth rate	Numerator: Live births <37 weeks of gestation. Denominator: Live births.
S3. Small-for-gestational age (INTERGROWTH)	Numerator: Infants <10% birth weight for GA by sex compared with INTERGROWTH neonatal birthweight standard.2 Denominator: Live births
S4. Low birth weight	Numerator: Newborns with birth weight (<72 hours of life) <2500 g. Denominator: Live births. We will also assess the outcome of birth weight <2000 g.
S5. Stillbirth rate	Numerator: Stillbirth/fetal death (≥28 weeks gestation) with no signs of life. Denominator: All live births and stillbirths
S6. Newborn head circumference	Head circumference of the infant measured at <72 hours of age.
S7. Newborn weight, length and head circumference for age Z-scores	Infant weight, length and head circumference for age z-scores measured at <72 hours of life, calculated using the INTERGROWTH neonatal standards for size at birth.
S8. Rate of weight gain in pregnancy	Maternal weight gain (kg) per week gestation in the second and third trimester.
S9. Maternal anaemia	Mean haemoglobin concentration in third trimester

BPD, biparietal diameter; CRL, crown rump length; FL, femur length; GA, gestational age.