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. 2021 Sep 14;19(9):1442–1467. doi: 10.2174/1570159X19666210726150432

Table 2.

Adverse effects recorded in a 12-week clinical study in which subjects were treated with either Bacopa monnieri or placebo, and as reported by Stough et al. [36].

Adverse Effect Bacopa Monnieri (300 mg/day) Placebo
Drowsiness 5% 4%
Allergies 14% 16%
Cold/flu symptoms 9% 28%
Skin rash 5% 12%
Skin itching 5% 12%
Headache 18% 28%
Tinnitus 9% 16%
Vertigo 9% 8%
Strange taste in mouth 14% 16%
Dry mouth 23% 16%
Palpitations 18% 8%
Abdominal pain 9% 8%
Appetite increase 18% 20%
Appetite reduction 0% 4%
Excessive thirst 18% 8%
Nausea 18% 4%
Indigestion 9% 4%
Constipation 9% 8%
Increased regularity of bowel movements 9% 4%
Increased frequency of urine 14% 8%
Muscular fatigue 14% 4%
Muscular pain 5% 8%
Cramps 5% 8%
Increase in felt stress 9% 12%
Decrease in felt stress 23% 28%
Improved mood 5% 8%
Worsened mood 5% 8%