TABLE 4.
Univariate and multivariate analyses for overall survival of CRC patients with liver metastasis.
| Characteristic | Univariate analysis | p value | Multivariate analysis | p value | ||
|---|---|---|---|---|---|---|
| RR | 95%CI | RR | 95%CI | |||
| Age | 0.73 | 0.39–1.37 | 0.33 | — | — | — |
| Gender | 1.28 | 0.69–2.37 | 0.43 | — | — | — |
| Differentiation | 1.52 | 0.73–3.19 | 0.26 | — | — | — |
| Tumor diameter (cm) | 1.24 | 0.67–2.29 | 0.49 | — | — | — |
| T stage | 8.32 | 1.14–60.59 | 0.04 | 0.67 | 0.62–7.23 | 0.74 |
| N stage | 4.41 | 1.36–14.31 | 0.01 | 0.14 | 0.03–0.74 | 0.02 |
| M stage | 6.18 | 2.19–17.37 | 0.00 | 0.06 | 0.01–0.35 | 0.00 |
| Clinical stage | 1.8 | 1.86–98.65 | 0.08 | 89.73 | 3.14–2,565.29 | 0.00 |
| CEA | 1.62 | 0.86–3.06 | 0.14 | — | — | — |
| miR-96 | 39.11 | 5.37–284.59 | 0.00 | 69.25 | 5.31–902.75 | 0.00 |
| miR-99b | 0.08 | 0.03–0.21 | 0.00 | 0.16 | 0.04–0.69 | 0.01 |
| miR-155 | 2.86 | 1.43–5.73 | 0.00 | 1.19 | 0.44–3.27 | 0.73 |
| let-7a | 2.44 | 1.19–5.00 | 0.015 | 0.61 | 0.25–1.46 | 0.26 |
| let-7b | 0.44 | 0.23–0.87 | 0.02 | 1.24 | 0.46–3.36 | 0.67 |
Note: The bold values is that the result of multivariate analysis is significant.