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. 2022 Jan 3;12:764130. doi: 10.3389/fphar.2021.764130

FIGURE 1.

FIGURE 1

Rb2 inhibited the atherosclerosis plaque development induced by miR-216a in mice. (A) Representative image of lesions in en face aorta evaluated by Oil red O staining. (B) Quantification of Oil red O–positive areas in the aortas cut lengthwise. (C) Representative image of HE staining in the thoracic aorta from the Ad-NC group, Ad-miR-216a group, Ad-NC + Rb2 group, and Ad-miR-216a + Rb2 group. Scale bar = 50 μM. (D) Quantification of the lesion area of the thoracic aorta from the Ad-NC group, Ad-miR-216a group, Ad-NC + Rb2 group, and Ad-miR-216a + Rb2 group. **p < 0.01, compared to the Ad-NC group; #p < 0.05, ##p < 0.01, compared to the Ad-miR-216a group. n = 5 for each group.