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. 2022 Jan 3;12:806740. doi: 10.3389/fgene.2021.806740

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Copyright © 2022 Zhang, Zhang and Min.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biological function of HS-related FB-1 cluster. (A) The clustering of the HS and normal skin (NS)-related FB-1 cells grouped by disease (HS vs NS) and graph-based classification (C1 vs C2), respectively. (B) The differential module score of myofibroblast cells between HS and NS, and C1 and C2. (C) The expression levels of myofibroblast cell marker genes including COL12A1, COL1A1, COL3A1, CTHRC1, and PCSK1N in the HB-1 cells. (D) The differential expression levels of the myofibroblast cell marker genes between HS and NS bulk samples.