FIGURE 7.

Accessory subunit NDUFA9. (A) The structure of CI (PDB: 6ZKC) in cartoon with the surface of NDUFA9 (lavender) shown, the core subunits colored as in Figure 1A and the accessory subunits grey. (B) M. musculus CI (PDB: 6G2J) and (C) Y. lipolytica CI (PDB: 6RFR) shown as transparent surfaces with NDUFA9 (NUEM), ND3 (sea green) and ND6 (cyan-blue) shown in cartoon. NADPH and lipids are shown as spheres. The C-terminal coils of NDUFA9 are colored red. The key residues interacting with ND6 are shown in stick representation. Accessory subunits that are not important for the discussion are omitted from the figures for clarity. Subunits are colored as in Figure 1 in all the structure figures unless stated otherwise. NDUFA9: lavender, ND3: sea green, ND6: cyan-blue.