TABLE 1.

Summary of MOG-Ab associated cerebral cortical encephalitis cases included in this study.

Case	Author/Year	Demographic statistics	Clinical symptoms				Imaging	Serum	Immunotherapy		Relapse	Outcome
		Age/Sex	Headache	Fever	Seizure	Paralysis	Lesion	MOG-Ab titer	HIMP	Other therapy
1	Jain/2021	31/F	Yes	No	Yes	No	Unilateral cortical	1:10	Yes	MM	No	Full recovery
2	Ogawa/2017	23/M	Yes	No	Yes	No	Unilateral cortical	1:256	No	No	No	Full recovery
3	Ogawa/2017	38/M	No	No	Yes	Yes	Unilateral cortical	1:1024	Yes	No	No	Full recovery
4	Ogawa/2017	38/M	No	No	Yes	Yes	Unilateral cortical	1:512	Yes	No	No	Full recovery
5	Ogawa/2017	36/M	No	No	Yes	No	Unilateral cortical	1:2048	Yes	No	No	Full recovery
6	Hamid/2018	Teens/M	Yes	No	Yes	No	Unilateral cortical	NR	Yes	No	Yes	Improved
7	Tao/2020	28/M	Yes	Yes	Yes	No	Unilateral cortical	1:10	Yes	No	No	Full recovery
8	Tao/2020	32/M	Yes	Yes	Yes	No	Unilateral cortical	1:10	Yes	MM	No	Full recovery
9	Katsuse/2020	44/F	No	No	No	No	Unilateral cortical	1:128	Yes	No	No	Full recovery
10	Otani/2020	22/F	Yes	Yes	Yes	No	Unilateral cortical	1:1024	No	No	No	Full recovery
11	Budhram/2020	21/F	Yes	No	Yes	No	Unilateral cortical	1:80	No	No	No	Improved
12	Russ/2020	11/F	No	Yes	Yes	Yes	Unilateral cortical	NR	Yes	RTX	Yes	Improved
13	Tian/2021	8/F	Yes	Yes	N0	No	Unilateral cortical	1:10	Yes	No	No	Full recovery
14	Tian/2021	10/F	Yes	No	Yes	Yes	Unilateral cortical	1:10	Yes	No	No	Full recovery
15	Budhram/2019	23/M	Yes	Yes	Yes	Yes	Unilateral cortical	NR	Yes	No	No	Full recovery
16	Fujimori/2020	31/M	Yes	No	No	No	Unilateral cortical	1:1024	Yes	No	No	Full recovery
17	Patterson/2019	39/F	Yes	Yes	No	No	Unilateral cortical	NR	Yes	CTX	No	Improved
18	Maniscalco/2021	18/F	No	No	Yes	Yes	Unilateral cortical	1:2560	Yes	RTX	No	Full recovery
19	Ahsan/2021	7/F	Yes	No	Yes	Yes	Unilateral cortical	1:40	No	IVIg	No	Improved
20	Nie/2021	19/F	Yes	Yes	Yes	No	Unilateral cortical	1:512	Yes	No	No	Full recovery
21	Chang/2021	34/M	Yes	No	Yes	No	Unilateral cortical	NR	Yes	No	No	Full recovery
22	Matoba/2020	29/F	Yes	No	No	Yes	Unilateral cortical	NR	Yes	No	No	Full recovery
23	Doig/2020	11/M	Yes	Yes	Yes	No	Bilateral cortical	NR	Yes	IVIg	No	Improved
24	Doig/2020	4/M	Yes	Yes	Yes	Yes	Unilateral cortical	NR	Yes	IVIg and PE	No	Improved
25	Takamatsu/2020	15/M	No	Yes	Yes	No	Unilateral cortical	NR	No	No	No	Improved
26	Kim/2020	44/M	No	Yes	No	No	Unilateral cortical	NR	Yes	No	No	Full recovery
27	Kim/2020	52/F	Yes	No	Yes	No	Unilateral cortical	NR	Yes	AZA	No	Full recovery
28	Haddad/2019	23/M	Yes	No	Yes	Yes	Unilateral cortical	1:1000	Yes	No	No	Full recovery
29	Stamenova/2021	31/F	Yes	Yes	Yes	No	Bilateral cortical	NR	Yes	AZA	No	Improved
30	Wang/2021	19/M	Yes	Yes	Yes	No	Unilateral cortical	1:32	Yes	MM	No	Full recovery
31	Wang/2021	23/M	Yes	No	Yes	No	Unilateral cortical	1:32	Yes	MM	No	Full recovery
32	Hochmeister/2020	52/F	Yes	No	No	No	Bilateral cortical	1:320	Yes	No	Death	Death
33	Ikeda/2018	29/F	No	Yes	Yes	No	Bilateral cortical	1:1024	Yes	No	No	Full recovery
34	patient 1	24/M	Yes	Yes	Yes	No	Bilateral cortical	1:100	Yes	IVIg	No	Full recovery
35	patient 2	25/M	Yes	Yes	Yes	Yes	Unilateral cortical	1:100	Yes	IVIg	No	Full recovery

F, female; M, male; MOG-Ab, myelin oligodendrocyte glycoprotein antibody; NR, not reported; HIMP, high-dose intravenous methylprednisolone; IVIg, intravenous immunoglobulin; PE, plasma exchange; RTX, rituximab; MM, mycophenolate mofetil; AZA, azathioprine; CTX, cyclophosphamide.