TABLE 4.

A comparison between the MD patient group and healthy control group in Hippocampal subfields.

	MD patients	Healthy control	p-value
Left
Hippocampal_tail	498 ± 88.4 mm3	533 ± 83.8 mm3	0.61
Subiculum-body	237 ± 33.4 mm3	248 ± 29.0 mm3	0.24
CA1-body	111 ± 22.6 mm3	119 ± 23.0 mm3	0.88
Subiculum-head	183 ± 33.5 mm3	192 ± 32.1 mm3	0.34
Hippocampal-fissure	152 ± 21.5 mm3	152 ± 29.5 mm3	0.63
Presubiculum-head	125 ± 18.6 mm3	133 ± 16.6 mm3	0.90
CA1-head	471 ± 67.0 mm3	506 ± 69.3 mm3	0.89
Presubiculum-body	151 ± 31.7 mm3	161 ± 28.5 mm3	0.59
Parasubiculum	50.2 ± 11.0 mm3	55.4 ± 10.3 mm3	0.12
Molecular-layer-HP-head	304 ± 40.6 mm3	327 ± 37.2 mm3	0.79
Molecular-layer-HP-body	207 ± 27.4 mm3	225 ± 22.3 mm3	0.42
GC-ML-DG-head	140 ± 20.9 mm3	153 ± 18.9 mm3	0.31
CA3-body	83.3 ± 14.1 mm3	87.7 ± 15.9 mm3	0.62
GC-ML-DG-body	123 ± 15.2 mm3	134 ± 13.4 mm3	0.10
CA4-head	117 ± 16.2 mm3	126 ± 14.9 mm3	0.46
CA4-body	112 ± 13.6 mm3	120 ± 13.1 mm3	0.23
Fimbria	80.3 ± 28.2 mm3	94.0 ± 20.1 mm3	0.10
CA3-head	109 ± 18.2 mm3	119 ± 18.8 mm3	0.30
HATA	50.1 ± 9.28 mm3	55.7 ± 8.51 mm3	0.25
Whole_hippocampal_body	1,104 ± 133 mm3	1,189 ± 97.6 mm3	0.61
Whole_hippocampal_head	1,549 ± 195 mm3	1,667 ± 182 mm3	0.70
Whole_hippocampus	3,151 ± 370 mm3	3,388 ± 293 mm3	0.81
Right
Hippocampal_tail	530 ± 95.9 mm3	565 ± 74.8 mm3	0.53
Subiculum-body	240 ± 36.2 mm3	245 ± 26.4 mm3	<0.01*
CA1-body	127 ± 23.5 mm3	131 ± 25.4 mm3	0.10
Subiculum-head	183 ± 31.8 mm3	197 ± 32.2 mm3	0.64
Hippocampal-fissure	170 ± 30.8 mm3	158 ± 25.9 mm3	0.06
Presubiculum-head	122 ± 19.3 mm3	133 ± 18.1 mm3	0.10
CA1-head	512 ± 72.1 mm3	545 ± 74.5 mm3	0.73
Presubiculum-body	141 ± 26.3 mm3	151 ± 23.6 mm3	0.39
Parasubiculum	47.2 ± 11.9 mm3	54.5 ± 12.6 mm3	0.04*
Molecular_layer_HP-head	319 ± 42.9 mm3	343 ± 42.1 mm3	0.83
Molecular_layer_HP-body	219 ± 31.4 mm3	235 ± 25.8 mm3	0.41
GC-ML-DG-head	150 ± 23.0 mm3	165 ± 21.2 mm3	0.61
CA3-body	94.8 ± 15.2 mm3	97.3 ± 16.3 mm3	0.11
GC-ML-DG-body	127 ± 16.6 mm3	137 ± 13.4 mm3	0.42
CA4-head	125 ± 17.1 mm3	135 ± 16.2 mm3	0.69
CA4-body	116 ± 15.0 mm3	122 ± 12.2 mm3	0.81
Fimbria	72.8 ± 30.6 mm3	94.8 ± 22.0 mm3	0.15
CA3-head	117 ± 20.4 mm3	128 ± 18.8 mm3	0.78
HATA	53.4 ± 10.0 mm3	56.9 ± 8.57 mm3	0.70
Whole-hippocampal-body	1,138 ± 149 mm3	1,214 ± 113 mm3	0.42
Whole-hippocampal-head	1,631 ± 207 mm3	1,758 ± 208 mm3	0.68
Whole-hippocampus	3,299 ± 410 mm3	3,537 ± 350 mm3	0.84

The volumes were normalized and given under: mean ± S.D, Age, sex, and total intracranial volume are covariates in analyses. Statistically Significant (i.e., p-values less than 0.05) is expressed asterisk.