TABLE 5A.
The HAMD scores and hippocampus subfields.
HAMD total score | HAMD subscale score |
|||||
Core | Sleep | Activity | Psychic | Somatic anxiety | ||
Left | ||||||
Hippocampal tail | 0.99 | 0.73 | 0.48 | 0.66 | 0.67 | 0.34 |
Subiculum body | 0.94 | 0.92 | 0.71 | 0.81 | 0.56 | 0.82 |
CA1 body | 0.95 | 0.59 | 0.84 | 0.75 | 0.70 | 0.64 |
Subiculum head | 0.28 | 0.78 | 0.012* | 0.75 | 0.86 | 0.55 |
Hippocampal fissure | 0.44 | 0.52 | 0.98 | 0.22 | 0.83 | 0.71 |
Presubiculum head | 0.47 | 0.90 | 0.0030* | 0.69 | 0.50 | 0.72 |
CA1 head | 0.41 | 0.84 | 0.37 | 0.66 | 0.82 | 0.91 |
Presubiculum body | 0.28 | 0.37 | 0.21 | 0.69 | 0.50 | 0.31 |
Parasubiculum | 0.86 | 0.88 | 0.24 | 0.55 | 0.53 | 0.90 |
Molecular layer HP head | 0.60 | 0.98 | 0.19 | 0.90 | 0.76 | 0.63 |
Molecular layer HP body | 0.71 | 0.97 | 0.48 | 0.83 | 0.46 | 0.95 |
GC ML DG head | 0.07 | 0.042* | 0.75 | 0.11 | 0.30 | 0.20 |
CA3 body | 0.58 | 0.43 | 0.77 | 0.52 | 0.85 | 0.21 |
GC ML DG body | 0.66 | 0.79 | 0.90 | 0.86 | 0.98 | 0.92 |
CA4 head | 0.08 | 0.07 | 0.48 | 0.16 | 0.34 | 0.29 |
CA4 body | 0.63 | 0.84 | 0.96 | 0.89 | 0.98 | 0.60 |
Fimbria | 0.07 | 0.10 | 0.84 | 0.31 | 0.29 | 0.15 |
CA3 head | 0.015* | 0.007* | 0.44 | 0.025* | 0.15 | 0.15 |
HATA | 0.38 | 0.16 | 0.025* | 0.09 | 0.91 | 0.31 |
Whole hippocampal body | 0.93 | 0.73 | 0.46 | 0.73 | 0.92 | 0.71 |
Whole hippocampal head | 0.94 | 0.54 | 0.13 | 0.63 | 0.98 | 0.51 |
Whole hippocampus | 0.999 | 0.58 | 0.20 | 0.61 | 0.92 | 0.44 |
Right | ||||||
Hippocampal tail | 0.55 | 0.52 | 0.67 | 0.74 | 0.19 | 0.65 |
Subiculum body | 0.95 | 0.92 | 0.97 | 0.52 | 0.43 | 0.68 |
CA1 body | 0.84 | 0.89 | 0.79 | 0.50 | 0.53 | 0.73 |
Subiculum head | 0.76 | 0.97 | 0.87 | 0.62 | 0.93 | 0.95 |
Hippocampal fissure | 0.98 | 0.61 | 0.08 | 0.50 | 0.76 | 0.74 |
Presubiculum head | 0.95 | 0.47 | 0.24 | 0.65 | 0.99 | 0.46 |
CA1 head | 0.44 | 0.67 | 0.83 | 0.45 | 0.93 | 0.63 |
Presubiculum body | 0.91 | 0.60 | 0.68 | 0.67 | 0.74 | 0.21 |
Parasubiculum | 0.59 | 0.20 | 0.48 | 0.32 | 0.28 | 0.40 |
Molecular layer HP head | 0.71 | 0.98 | 0.83 | 0.64 | 0.94 | 0.97 |
Molecular layer HP body | 0.97 | 0.82 | 0.84 | 0.77 | 0.60 | 0.93 |
GC ML DG head | 0.30 | 0.23 | 0.72 | 0.72 | 0.29 | 0.13 |
CA3 body | 0.70 | 0.67 | 0.91 | 0.88 | 0.32 | 0.67 |
GC ML DG body | 0.43 | 0.49 | 0.70 | 0.52 | 0.43 | 0.34 |
CA4 head | 0.22 | 0.20 | 0.90 | 0.61 | 0.15 | 0.15 |
CA4 body | 0.32 | 0.50 | 0.63 | 0.57 | 0.39 | 0.19 |
Fimbria | 0.12 | 0.47 | 0.75 | 0.77 | 0.59 | 0.12 |
CA3 head | 0.46 | 0.23 | 0.23 | 0.46 | 0.29 | 0.21 |
HATA | 0.030* | 0.0052* | 0.31 | 0.0066* | 0.19 | 0.0087* |
Whole hippocampal body | 0.61 | 0.60 | 0.91 | 0.94 | 0.43 | 0.72 |
Whole hippocampal head | 0.98 | 0.61 | 0.73 | 0.96 | 0.63 | 0.63 |
Whole hippocampus | 0.72 | 0.53 | 0.74 | 0.97 | 0.38 | 0.62 |
All data are p-values. Age, sex and total intracranial volume are covariates in analyses. Statistically Significant (i.e., p-value less than 0.05) is expressed asterisk.