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. 2022 Jan 7;20:496–507. doi: 10.1016/j.csbj.2022.01.004

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Topological characteristics of proportional and non-proportional genes in TCGA pan-cancer cohorts. (A) Betweenness of proportional and non-proportional genes; (B) Closeness of proportional and non-proportional genes; (C) Degree of proportional and non-proportional genes; (D & E) Gene interaction networks in GBM and LGG; (F) Proportion of gene CPH model that assumption violated PH in the 5 important biological processes. CPH, Cox proportional hazard regression; PH, proportional hazard; TCGA, The Cancer Genome Atlas.