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. 2021 Nov 1;83(12):1933–1942. doi: 10.1292/jvms.21-0464

Fig. 7.

Fig. 7.

Developed and residual scar lesions in the abdominal wall model. A: Multi-nodular/spherical-like structured lesions in the abdominal wall model developed on day 21. B: The scar lesion on day 21 shows massive collagen deposition, which is hazy and hyalinized in hematoxylin and eosin staining. C: Picrosirius red staining: The fibrous lesion that developed in the abdominal wall model forms a storiform pattern (left), in which thick collagen bundles are primarily stained in orange color, showing type 1 collagen. In the back skin splint model (right), thin collagen bundles were deposited in the granulation tissue on day 21, many of which were stained green, showing type 3 collagen. D: In the abdominal wall model, an apparent collagen-rich scar lesion (arrows) remained after 87 days of the study, which was deformed and different from that in the normal control in a similar tissue site (left).